Top 100 Secrets
These secrets are 100 of the top board alerts. They summarize the concepts, principles, and most salient details of neurology.
1. The first step in treating patients with neurologic disease is to localize the lesion.
2. Myopathies cause proximal symmetric weakness without sensory loss.
3. Neuromuscular junction diseases cause fatigability.
4. Peripheral neuropathies cause distal asymmetric weakness with atrophy, fasciculations, sensory loss, and pain.
5. Radiculopathies cause radiating pain.
6. Spinal cord disease causes a triad of distal symmetric weakness, sphincter problems, and a sensory level.
7. A unilateral lesion within the brain stem often causes “crossed syndromes,” in which ipsilateral dysfunction of one or more cranial nerves is accompanied by hemiparesis and/or hemisensory loss on the contralateral body.
8. Cerebellar disease causes ataxia and an action tremor.
9. In the brain, cortical lesions may cause aphasia, seizures, and partial hemiparesis (face and arm only), while subcortical lesions may cause visual field cuts, dense numbness of primary sensory modalities, and more complete hemiparesis (face, arm, and leg).
10. The brain is isolated from the rest of the body by the blood-brain barrier.
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